Clinical and neuropathologic differences between amnestic and nonamnestic MCI Lead Investigator: Ron Petersen Institution : Mayo E-Mail : peter8@mayo.edu Proposal ID : 635 Proposal Description: We are working to update the neuropathology of MCI, in order to make recommendations for the next round of Alzheimer???s disease clinical criteria. We have currently evaluated clinical differences and neuropathologic differences amongst Mayo Clinic study participants, but thought that a validation set through NACC would benefit our project and demonstrate the utility of NIH-funded NACC center. Our overall goal is to identify clinical and neuropathologic differences between amnestic and nonamnestic MCI.